Line the base of a 16cm round spring form tin with baking paper.
Open the panettone and peel off the paper completely. Slice off 3 x 8cm thick round starting from the base of the cake and place the bottom layer into the lined tin. Brush with some Amaretto.
Meanwhile, place egg white into the Thermomix bowl and whip 4 min/37º/Butterfly/speed 3.
Add 30g sugar 1 teaspoon at a time through the hole in the lid. Remove from the Thermomix bowl into a large mixing bowl and set aside.
Without cleaning, place egg yolks, 70g sugar and a splash of Amaretto or orange juice into the Thermomix bowl and whip 4 min/37°C/Butterfly/speed 3.
Cool slightly before adding in the very cold mascarpone, vanilla bean paste and orange oil. Whip until holding soft peaks, 20-40 sec/Butterfly/speed 4. Mascarpone will whip faster than cream, so be careful. Do not over whip or the mascarpone may split.
Add Fruity Pear Mince and mascarpone mix to egg whites and fold through gently using a large metal spoon or spatula.
Top the first layer of panettone with plenty of the mascarpone mixture. Press another round of the cake on top, pushing the filling down the sides if there is a gap between the circumference of your cake and tin. Brush that layer with Amaretto as well, top with mixture and repeat with final layer.
Refrigerate for at least 6 hours. Longer is OK as the flavours will deepen over time.
This can be made up to 3 days in advance of eating it.